Obesity Is Not Associated with Impaired Immune Response to Influenza Vaccination in HIV-Infected Persons

Table 3

Proportions with seroconversion and seroprotection after vaccination among participants with CD4 cell counts > 200 cells/μL () and CD4 cell counts > 500 cells/μL ().

Participants with CD4 > 200 cells/μL ()	Nonobese (BMI < 30 kg/m^2); ()	Obese (BMI ≥ 30 kg/m^2); ()	value
Seroconversion, % (95% CI)
H1N1	70 (61–79)	62 (47–76)	0.31
H3N2	79 (71–87)	81 (69–92)	0.80
Influenza B	45 (36–55)	49 (34–64)	0.69
Seroprotection, % (95% CI)
H1N1	94 (89–98)	89 (80–98)	0.36
H3N2	98 (96–100)	98 (94–100)	0.90
Influenza B	92 (87–97)	85 (74–96)	0.20
Participants with CD4 > 500 cells/μL ()	Nonobese (BMI < 30 kg/m^2); ()	Obese (BMI ≥ 30 kg/m^2); ()	value
Seroconversion, % (95% CI)
H1N1	68 (56–81)	75 (56–94)	0.56
H3N2	72 (60–84)	79 (62–97)	0.52
Influenza B	35 (22–48)	38 (17–58)	0.84
Seroprotection, % (95% CI)
H1N1	93 (85–100)	96 (87–100)	0.59
H3N2	98 (94–100)	100 (100–100)	0.50
Influenza B	94 (88–100)	92 (80–100)	0.64

BMI: body mass index; CI: confidence interval.