Prevalence and Clinical Spectrum of Liver Disease in Nepalese HIV-Sero-Positive Patients Undergoing Antiretroviral Therapy: A Cross-Sectional Hospital Based Study

Table 4

Patients characteristics and pattern of liver injury.

	Pattern of liver toxicity
Gender	Hepatocellular	Cholestatic	Mixed	Normal	Total patients
					Gender							0.026
Male	43 (29.86)	10 (6.94)	4 (2.77)	23 (15.97)	80
Female	17 (11.80)	6 (4.16)	2 (1.38)	36 (25.00)	61
Transgender	1 (0.69)	0 (0.00)	0 (0.00)	2 (1.38)	3
CD4 cells						0.382
<50	4 (2.77)	1 (0.69)	0 (0.00)	2 (1.38)	7
>50–<100	2 (1.38)	0 (0.00)	0 (0.00)	8 (5.55)	10
100–200	17 (35.71)	3 (1.30)	1 (0.60)	12 (13.88)	33
>200–500	35 (11.88)	10 (6.94)	5 (3.47)	38 (26.38)	88
>500	3 (2.08)	2 (1.38)	0 (0.00)	1 (0.69)	6
Coinfection						0.18
HCV	4 (2.77)	1 (0.69)	0 (0.00)	3 (2.08)	8
HCV + HBV	1 (0.69)	0 (0.00)	0 (0.00)	0 (0.60)	1
TB	8 (5.55)	0 (0.00)	0 (0.00)	1 (0.69)	9
None	48 (33.33)	15 (10.41)	6 (4.16)	57 (39.58)	126
Alcoholics						0.068
Yes	29 (20.13)	3 (2.08)	3 (2.08)	18 (12.50)	53
No	32 (2.08)	13 (9.08)	3 (2.08)	43 (29.06)	91
ART						0.129
NVP	17 (11.80)	6 (4.16)	1 (0.69)	27 (18.75)	51
EFV	41 (28.47)	7 (4.86)	5 (3.47)	29 (2013)	82
Others	3 (2.08)	3 (2.08)	0 (0.00)	5 (3.47)	11