Prediction of CD4 T-Lymphocyte Count Using WHO Clinical Staging among ART-Naïve HIV-Infected Adolescents and Adults in Northern Ethiopia: A Retrospective Study

Table 3

The relationship between CD4 T-lymphocyte count and WHO stages among ART-naïve HIV-infected adolescents and adults in northern Ethiopia, n = 19525.

WHO stage	CD4 T-lymphocyte count		Total
	<200 cell/μl	≥200 cell/μl
I and II	9,122 (94.17)	9482 (96.38)	18,604 (95.28)
III and IV	565 (5.83)	356 (3.62)	921 (4.72)
Total	9,687 (100.00)	9,838 (100.00)	19,525 (100.00)
Sensitivity	94.17%
Specificity	3.62%
Positive predictive value (PPV)	49.03%
Negative predictive value (NPV)	3.62%
	<350 cell/mm^3	≥350 cell/mm^3
I and II	14,103 (94.75)	4501 (97.00)	18604 (95.28)
III and IV	782 (5.25)	139 (3.00)	921 (4.72)
Total	14,885 (100.00)	4,640 (100.00)	19,525 (100.00)
Sensitivity	94.75%
Specificity	3.00%
Positive predictive value (PPV)	75.81%
Negative predictive value (NPV)	15.09
	<500 cell/mm^3	≥500 cell/mm^3
I and II	16432 (95.03)	2172 (97.27)	18604 (95.28)
III and IV	860 (4.97)	61 (2.73)	921 (4.72)
Total	17,292 (100.00)	2,233 (100.00)	19,525 (100.000)
Sensitivity	95.03%
Specificity	2.73%
Positive predictive value (PPV)	88.32%
Negative predictive value (NPV)	6.62%