AIDS Research and Treatment / 2020 / Article / Tab 4

Research Article

Overweight and Obesity among Recipients of Antiretroviral Therapy at HIV Clinics in Gaborone, Botswana: Factors Associated with Change in Body Mass Index

Table 4

Characteristics and bivariate analysis of study participants by BMI at their last clinic visit (BMI-2) at Princess Marina Hospital and Bontleng anti-retroviral therapy clinics in Botswana categorized as underweight, normal and overweight/obesity ().

CharacteristicsBMI after patients’ initiation on ART (BMI-2)
TotalUnderweightNormal BMI††Overweight/obesityUOR-value

Age after ART initiation [years, mean ± SD]47.6 ± 9.650.1 ± 14.147.6 ± 9.647.3 ± 8.50.180

ART regimen
Second/third-line, (%)208 (39.2)13 (29.5)101 (43.3)88 (36.5)1
First-line, (%)323 (60.8)31 (70.5)132 (56.7)153 (63.5)1.20.250
Duration of exposure to ART (months, mean ± SD)84.9 ± 29.791.7 ± 28.087 ± 30.181 ± 29.30.190

Gender
Male, (%)163 (30.7)28 (63.6)89 (38.2)45 (18.7)1
Female, (%)368 (69.3)16 (36.4)144 (61.8)196 (81.3)3.00.001

CD4 cell count/mm3 at last clinic visit
Median (IQR)515 (310–691)444 (270–597)513 (375–686)577 (416–732)0.001

CD4 cell count/mm3 categories at last clinic visit
≥350, (%)421 (79.3)22 (50.0)183 (78.5)216 (89.6)1
Nadir (0–200), (%)34 (6.4)8 (18.2)17 (7.3)8 (3.3)0.290.003
201–349, (%)76 (14.3)14 (31.8)33 (14.2)17 (7.1)0.270.001

DRC
Absent, (%)442 (83.2)40 (90.9)201 (86.3)189 (78.4)1
Present, (%)89 (16.8)4 (9.1)32 (13.7)52 (21.6)1.880.007

ART = antiretroviral therapy; BMI = body mass index; overweight/obesity = overweight or obesity and morbidly obese; UOR = unadjusted odds ratio; DRC = diabetes-related comorbidity; SD = standard deviation; ; reference group; ††outcome of interest.

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