AIDS Research and Treatment

AIDS and HIV Infection after Thirty Years


Publishing date
01 Jun 2012
Status
Published
Submission deadline
02 Dec 2011

1National Institute for Infectious Diseases Lazzaro Spallanzani, Via Portuense 292, 00149 Rome, Italy

2AIDS Research Institute, University of California at San Francisco, CA, USA

3Division of Infectious Diseases, Department of Medicine, Karolinska Institute, Stockholm, Sweden

4Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, United Nations Road, Dar es Salam, Tanzania

5University of Rome “La Sapienza” Medical School; I.N.M.I. “L. Spallanzani” I.R.C.C.S., Rome, Italy


AIDS and HIV Infection after Thirty Years

Description

AIDS, caused by HIV, first appeared in Western countries in 1981 as a disease leading to a high death rate approaching 100% after 5–10 years of the diagnosis. After 3 decades, following many innovative approaches, AIDS has become in many industrialized countries a chronic disease with a survival for many years following infection. Moreover, there are indications that most of the casualties are due to tumors or organ failures, only indirectly linked to HIV infection. Several of these conditions result from the antiretroviral therapy (ART) or ongoing virus replication. Certain factors, still to be fully understood, appear responsible for the prognostic improvement. Among the first are undoubtedly the availability of laboratory and therapeutic tools that permit an early diagnosis and an effective treatment. Further improvements in treating HIV infection, such as directions at a cure, would be made possible only by unmasking the virus from sanctuaries that are presently out of reach by both drugs. Another important step is making the therapies more available to resource-limited countries, where they are not widely distributed. In addition, probably the most notable, and at the same time most intriguing, would be the possible evolution of HIV toward attenuation, leading to a more benign course of the disease. This event would in fact be beneficial to both the virus, which could have a longer period of transmission, and the host, with an extended survival, and today it is hypothetical and merits attention. For this special edition, potential topics on HIV/AIDS include, but are not limited to:

  • HIV infection in 2011. Where are we going?
  • HIV clades; toward globalization?
  • Viral persistence: latency, compartmentalization, or both
  • Novel therapeutical strategies toward eradication
  • Is epidemiology changing?
  • Progresses in innate immunity
  • Progresses in adaptive immunity
  • Is an effective vaccine feasible?
  • Can the costs be reduced?
  • 1990-2010: final causes of death in HIV patients

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/art/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 731983
  • - Editorial

AIDS and HIV Infection after Thirty Years

Giuseppe Ippolito | Jay A. Levy | ... | Ferdinando Dianzani
  • Special Issue
  • - Volume 2012
  • - Article ID 595762
  • - Review Article

Cost-Effectiveness of Antiretroviral Therapy for Multidrug-Resistant HIV: Past, Present, and Future

Marianne Harris | Bohdan Nosyk | ... | Julio Montaner
  • Special Issue
  • - Volume 2012
  • - Article ID 869891
  • - Review Article

Pharmacists’ Research Contributions in the Fight against HIV/AIDs

Alexis E. Horace
  • Special Issue
  • - Volume 2012
  • - Article ID 352753
  • - Research Article

CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria

Akinsegun Akinbami | Adedoyin Dosunmu | ... | Olanrewaju Arogundade
  • Special Issue
  • - Volume 2012
  • - Article ID 581531
  • - Clinical Study

Comparison of the Minimental State Examination Scale and the International HIV Dementia Scale in Assessing Cognitive Function in Nigerian HIV Patients on Antiretroviral Therapy

O. Olajumoke Oshinaike | A. Akinsegun Akinbami | ... | A. Mustapha Danesi
  • Special Issue
  • - Volume 2012
  • - Article ID 873171
  • - Clinical Study

Oral HIV-Associated Kaposi Sarcoma: A Clinical Study from the Ga-Rankuwa Area, South Africa

Razia A. G. Khammissa | Liron Pantanowitz | Liviu Feller
  • Special Issue
  • - Volume 2012
  • - Article ID 620962
  • - Clinical Study

A Comparison of Chronic Periodontitis in HIV-Seropositive Subjects and the General Population in the Ga-Rankuwa Area, South Africa

Razia Khammissa | Liviu Feller | ... | Johan Lemmer
  • Special Issue
  • - Volume 2012
  • - Article ID 418630
  • - Review Article

Thirty Years Later: Pregnancies in Females Perinatally Infected with Human Immunodeficiency Virus-1

Martina L. Badell | Michael Lindsay
  • Special Issue
  • - Volume 2012
  • - Article ID 708456
  • - Research Article

Virological Response in Cerebrospinal Fluid to Antiretroviral Therapy in a Large Italian Cohort of HIV-Infected Patients with Neurological Disorders

Maria Letizia Giancola | Patrizia Lorenzini | ... | Andrea Antinori
  • Special Issue
  • - Volume 2012
  • - Article ID 161584
  • - Review Article

Thirty Years with HIV Infection—Nonprogression Is Still Puzzling: Lessons to Be Learned from Controllers and Long-Term Nonprogressors

Julie C. Gaardbo | Hans J. Hartling | ... | Susanne D. Nielsen
AIDS Research and Treatment
 Journal metrics
Acceptance rate17%
Submission to final decision90 days
Acceptance to publication33 days
CiteScore3.200
Impact Factor-
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