Research Article

Influence of Different Doses of Levofloxacin on Antioxidant Defense Systems and Markers of Renal and Hepatic Dysfunctions in Rats

Table 3

Effects of levofloxacin treatments on plasma lipid profile in rats.

TreatmentTotal cholesterol (mg/dL)HDL-cholesterol (mg/dL)LDL-cholesterol (mg/dL)Triglyceride (mg/dL)

Control68 ± 3.3038 ± 4.344.5 ± 0.513.5 ± 0.35
LFX-187.8 ± 3.29 (29%)*51 ± 2.16 (34%)*6.6 ± 0.8 (23%)*20 ± 1.0 (54%)*
LFX-2102 ± 2.21 (50%)*55 ± 3.30 (45%)*7.8 ± 0.6 (56%)*23.5 ± 0.78 (77%)*
LFX-3113 ± 1.70 (66%)*58 ± 3.87 (53%)*9.4 ± 0.7 (83%)*28 ± 1.7 (115%)*

The values are means ± SD for five rats in each group. *Significantly different from the control, < 0.05. Values in parenthesis represent percentage (%) of the increase.