Influence of Different Doses of Levofloxacin on Antioxidant Defense Systems and Markers of Renal and Hepatic Dysfunctions in Rats

Table 4

Effects of levofloxacin treatments on hepatic superoxide dismutase (SOD) and catalase in rats.

Treatment	Superoxide dismutase (Units/mg protein)	Catalase (µmol H2O2 consumed/min/mg protein)
Control	7.52 ± 0.10	0.63 ± 0.01
LFX-1	5.8 ± 0.23 (23%)^*	0.58 ± 0.01 (8%)^*
LFX-2	3.5 ± 0.23 (52%)^*	0.49 ± 0.03 (14%)^*
LFX-3	2.7 ± 0.38 (66%)^*	0.33 ± 0.02 (25% )^*

The values are means ± SD for five rats in each group. ^*Significantly different from the control, < 0.05. Values in parenthesis represent percentage (%) of the increase.