Overview of Contemporary Penile Rehabilitation Therapies

Table 1

Summary table of penile rehabilitation trials.

Authors	Year published	Treatment regiment	Study design	𝑁	Significant findings
Schwartz et al.	2004	QOD PDEi	Prospective	21	No loss of smooth muscle in 50 mg group, gain of smooth muscle in 100 mg group
Bannowski et al.	2008	Daily PDEi	Prospective, randomized control	41	Treatment group had significantly higher IIEF and higher spontaneous erection rates
McCullough et al.	2008	Daily PDEi	Prospective, randomized, placebo control	54	Treatment groups had higher return of rigidity, higher rate of spontaneous erections
Raina et al.	2006	Daily VED	Prospective, randomized control	109	Improved sexual satisfaction, higher rate of spontaneous erections
Köhler et al.	2007	Daily VED (10 mins), immediate versus delayed	Prospective, randomized	28	Delayed use of VED did not affect sexual satisfaction once use began. There is no statistical significance in penile shrinkage once VED started
Montorsi et al.	1999	ICI 3 times weekly	Prospective, randomized control	30	Higher percentage of treatment group having spontaneous erections
Mulhall et al.	2005	ICI or PDEi to achieve erections 3 times weekly	Prospective, control	132	Treatment groups had 2.7 times the rate of spontaneous erections, statistically higher IIEF scores
Nandipati et al.	2006	Daily PDEi and ICI 2-3 times week	Prospective	22	Assisted early sexual activity and satisfaction. Addition of PDEi allows lower dose of ICI.