Clinical Study

Predictors of Response to Intradetrusor Botulinum Toxin-A Injections in Patients with Idiopathic Overactive Bladder

Table 1

Comparison of responders and nonresponders in patients with OAB-Dry and OAB-Wet: demographic and urodynamic data.

OAB-DRYOAB-WET
Parameter (units)RespondersNonresponders š‘ƒ -valueRespondersNonresponders š‘ƒ -value

š‘ 155NA1710NA
PVR (mL) 2 4 Ā± 3 6 2 9 Ā± 3 6 .76 2 4 Ā± 2 5 2 4 Ā± 3 3 .93
MCC (mL) 2 4 2 Ā± 1 1 2 2 6 3 Ā± 1 2 4 .66 2 4 8 Ā± 1 4 7 2 2 7 Ā± 1 0 0 .71
pDetMax (cm H2O) 4 0 Ā± 1 7 3 4 Ā± 1 8 .47 4 9 Ā± 2 4 2 9 Ā± 1 6 .06
pVesMax (cm H2O) 6 2 Ā± 2 7 5 1 Ā± 1 2 .38 7 4 Ā± 3 2 6 0 Ā± 3 0 .24
Voided vol (mL) 2 7 9 Ā± 1 4 8 2 2 6 Ā± 1 7 4 .51 2 2 3 Ā± 1 5 5 1 7 1 Ā± 9 7 .24
pDetQMax (cm H2O) 2 4 Ā± 1 2 4 3 Ā± 4 8 .58 3 5 Ā± 2 0 2 3 Ā± 2 0 .23
Q Max (mL/sec) 1 4 Ā± 6 1 3 Ā± 1 1 .91 1 5 Ā± 1 1 1 4 Ā± 7 .99
DO+5/151/5.5812/178/10.99
100 Units64.1584.77
150 Units91114
Age 4 8 Ā± 1 5 5 9 Ā± 1 3 .11 5 5 Ā± 1 5 6 8 Ā± 1 3 .03
Number of males50.2010.89

PVR: postvoid residual; MCC: maximum cystometric capacity; pDetMax: detrusor maximum pressure; pVesMax: vesical maximum pressure; vol: volume; Qmax: maximum flow rate; DO+: presence of detrusor overactivity; mL: milliliters; cm H2O: centimeters of water; mL/sec: milliliters per second.