Tumoral Prostate Shows Different Expression Pattern of Somatostatin Receptor 2 (SSTR2) and Phosphotyrosine Phosphatase SHP-1 (PTPN6) According to Tumor Progression
Figure 2
Distribution of SHP-1 on human prostate carcinoma. Photographies show characteristic pattern of SHP-1 immunostaining on tumor zones: (a) Gleason H; (b) Gleason M; (c) Gleason L. (d) Percentages of cases classified for immunostaining intensity and Gleason grade. Tissues were immunostained for SHP-1 was and the immunostaining intensity was classified as “+++” if the intensity was the same of positive control, “++” or “+” if the intensity was less than positive control, and “−” if absent. Gleason L: low-grade adenocarcinomas zones, Gleason grade 1 and 2. Gleason I: intermediate-grade adenocarcinomas zones, Gleason grade 3. Gleason H: high-grade adenocarcinomas zone, Gleason grade 4 and 5.