Clinical Study

Treatment Strategy According to Findings on Pressure-Flow Study for Women with Decreased Urinary Flow Rate

Table 3

Change in parameters after distigmine bromide treatment in patients without bladder outlet obstruction.

ParametersPretreatmentPosttreatmentP-value(1)

Clinical parameters ( )
IPSS17.8 (8.3)(2)5.2 (4.8).028
QOL index5.3 (0.5)1.3 (1.0).028
Uroflowmetry
Voided volume (mL)223.7 (54.6)245.7 (124.6).753
Maximum flow rate (mL/sec)8.1 (2.3)13.1 (4.3).046
Average flow rate (mL/sec)3.7 (1.0)6.8 (1.8).028
Postvoid residual urine volume (mL)71.3 (69.4)45.0 (61.0).249

Pressure flow studies ( )
Maximum flow rate (mL/sec)8.3 (2.9)13.3 (0.6).109
Pressure at maximum flow (cm water)31.0 (5.6)33.0 (8.7) .999
Urethral resistance factor (cm water)20.2 (1.3)15.8 (2.1).109
Maximum watts factor (W/m2)6.1 (2.5)8.9 (0.2).109

(1)Wilcoxon signed-rank test
(2)Mean (standard deviation).