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Advances in Urology
Volume 2011, Article ID 820816, 8 pages
Review Article

An Overview of the Clinical Use of Antimuscarinics in the Treatment of Overactive Bladder

Urodynamic Urology Unit, Department of Urology, Medical School, University of Patras, 26500 Patra, Greece

Received 26 February 2011; Accepted 13 April 2011

Academic Editor: Yasuhiko Igawa

Copyright © 2011 Anastasios Athanasopoulos and Konstantinos Giannitsas. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Overactive bladder is a common and bothersome condition. Antimuscarinic agents, as a class, are the cornerstone of medical treatment of overactive bladder. They offer significant improvements in symptoms and patients’ quality of life. Antimuscarinics are generally well tolerated with mild and predictable side effects. Available antimuscarinics have small, yet statistically significant, differences in their efficacy and tolerability profiles. In clinical practice, finding the agent that offers the optimum balance of efficacy and side effects for an individual patient remains the major challenge.