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Advances in Urology
Volume 2012, Article ID 142135, 10 pages
Review Article

Muscle Invasive Bladder Cancer: From Diagnosis to Survivorship

1Department of Urology and Oncological Science, Mount Sinai School of Medicine, New York, NY 10029-6574, USA
2Michael E. DeBakey VA Medical Center, University of Houston-Downtown and Baylor College of Medicine, Houston, TX 77030-4298, USA
3Department of Urology, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI 48109-0944, USA
4Department of Urology, Tawam Hospital, 15258 Al Ain, UAE

Received 5 April 2012; Accepted 16 May 2012

Academic Editor: Trinity J. Bivalacqua

Copyright © 2012 N. E. Mohamed et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Bladder cancer is the fifth most commonly diagnosed cancer and the most expensive adult cancer in average healthcare costs incurred per patient in the USA. However, little is known about factors influencing patients' treatment decisions, quality of life, and responses to treatment impairments. The main focus of this paper is to better understand the impact of muscle invasive bladder cancer on patient quality of life and its added implications for primary caregivers and healthcare providers. In this paper, we discuss treatment options, side effects, and challenges that patients and family caregivers face in different phases along the disease trajectory and further identify crucial areas of needed research.