Muscle Invasive Bladder Cancer: From Diagnosis to Survivorship

Table 1

Quality-of-life instruments. (With permission from Lee et al. [44]).

Instrument	Institution	Domains	Validated	Reliable	Cancer specific	Bladder cancer specific	No. of items
BCI [33, 45]	University of Michigan	Urinary; Bowel; Sexual function	Yes	Yes	Yes	Yes	34
FACT-VCI [46]	Vanderbilt University	See FACT-G; Urinary; Bowel; Sexual function	Yes	Yes	Yes	Yes (limited tocystectomy)	45
QLQ-BLM 30 module [47]	EORTC	Urinary; Bowel; Sexual function	Ongoing studies	Ongoing studies	Yes	Yes (muscle-invasive disease)	30
QLQ-BLS 24 Module [45]	EORTC	Urinary; Bowel; Sexual function	Ongoing studies	Ongoing studies	Yes	Yes (nonmuscle-invasive disease)	24
FACT-BL [48]	FACIT	See FACT-G; Limited urinary; Limited bowel; Limited sexual function	Ongoing studies	Ongoing studies	Yes	Yes	39
FACT-G [49]	FACIT	Physical; Social; Emotion; Function	Yes	Yes	Yes	No	27
QLQ-C30 [47]	EORTC	5 Functional scales; 3 Symptom scales; 1 Global health/QOL scale	Yes	Yes	Yes	No	30
SF-36 [34]	RAND	8 Domains including; Physical; Mental; Social function; Emotional	Yes	Yes	No	No	36

BCI: Bladder Cancer Index; EORTC: European Organization for the Research and Treatment of Cancer.
FACIT: The Functional Assessment of Chronic Illness Therapy.
FACT-BL: Functional Assessment of Cancer Therapy—Bladder Cancer (Extension of the FACT-G + 12 additional bladder cancer-specific items including incontinence, diarrhea, body image, sexual function, and stoma care).
FACT-G: Functional Assessment of Cancer Therapy General.
FACT-VCI: Functional Assessment of Cancer Therapy—Vanderbilt Cystectomy Index (Extension of the FACT-G + 17 additional bladder cancer and treatment specific items).
QLQ-C30: EORTC Quality-of-Life Core Questionnaire.
QLQ-BLM30: EORTC Quality-of-Life Core Questionnaire—Bladder Cancer Muscle Invasive (Extension of the QLQ-C30 + 30 additional bladder cancer-specific items; http://www.eortc.be/home/qol/files/SCManualQLQ-C30.pdf).
QLQ-BLS24: EORTC Quality-of-Life Core Questionnaire—Bladder Cancer Superficial (Extension of the QLQ-C30 + 24 additional bladder cancer-specific items; http://www.eortc.be/home/qol/files/SCManualQLQ-C30.pdf).
RAND Corporation: Research ANd Development.
SF-36: Medical Outcomes Study 36-Item Short Form.