Clinical Significance of ErbB Receptor Family in Urothelial Carcinoma of the Bladder: A Systematic Review and Meta-Analysis

Table 4

Co-expression of ErbB receptor family as a marker for bladder cancer prognosis.

Study name	Methods	Pts no.	Study subject	Significant co-expression pattern for
				Recurrence	Survival
[5]	IHC	245	T0–4	EGFR-ErbB2-ErbB3∗	EGFR-ErbB2
					ErbB2-ErbB3
[16]	IHC	184	T0–4	Not significant	High EGFR + low ErbB4
[28]	RT-PCR	88	T0–4	Not done	High EGFR + low ErbB3 or ErbB4
					High ErbB2 + low ErbB3 or ErbB4

^∗𝑃=0.075.