Calculated Tumor Volume Is an Independent Predictor of Biochemical Recurrence in Patients Who Underwent Retropubic Radical Prostatectomy

Table 1

Preoperative clinicopathological parameters.

	All patients (n = 255)	Biochem. recur. (+) (n = 77)	Biochem. recur. (−) (n = 178)	P value
Age	67.4±5.8	67.1±5.4	67.6±5.9	n.s.^§
PSA at biopsy (ng/mL)
Mean ± SD	10.9±7.2	14.1±9.9	9.6±5.2	<0.001^§
10 or less	151	35	116
10–20	84	28	56
Greater than 20	20	14	6	<0.001*
Biopsy Gleason score
6 or less	144	32	112
7	63	20	43
8–10	25	9	16
Unknown	23	9	14	<0.001*
Clinical stage
T1	151	38	113
T2	102	38	64
T3	2	1	1	0.001*
Calculated cancer volume (mL)
2.0 or less	112	17	95
2.0–4.0	47	17	30
Greater than 4.0	31	20	11
unknown	65	23	42	<0.001*
Mean ± SD	2.48±2.38	4.01±3.38	1.88±1.45	<0.001^§
% positive biopsy core
Less than 34	158	38	120
34–50	22	6	16
50 or greater	66	32	34
unknown	9	1	8	0.001*

Biochem. recur.: Biochemical recurrence. *Chi-square test and ^§Mann Whitney U test.