Monitoring Detrusor Oxygenation and Hemodynamics Noninvasively during Dysfunctional Voiding

Figure 1

A composite graph of UDS data with NIRS parameters total hemoglobin (tHb) deoxygenated hemoglobin (HHb) and oxygenated hemoglobin (O₂Hb) and EMG in a 64-year-old man. He had a 5-year history of increasing obstructive LUTS, had failed medical therapy, and complained of difficulty initiating urination, a weak stream, and slow flow. As Pdet increases prior to uroflow, there is a decrease in O₂Hb reflected by a fall in tHb and HHb begins to rise. During uroflow, this positive trend in HHb increases, some rise in O₂Hb is evident following Qmax but the associated rise in tHb predominantly reflects a greater rise in HHb concentration. This implies an imbalance in oxygen supply and demand during voiding.