Clinical Study
Proximal Hypospadias Repair Outcomes in Patients with a Specific Disorder of Sexual Development Diagnosis
Table 2
Anatomy, procedure, and outcomes comparison.
| | Group 1: proximal hypospadias with a specific DSD diagnosis () | Group 2: 46,XY proximal hypospadias without a specific DSD diagnosis () | value |
| Mean age at initial hypospadias repair (years) | 2.37 | 1.53 | |
| Meatal location | | | | Proximal shaft | 2 (11.8) | 16 (18.8) | | Penoscrotal | 3 (17.6) | 38 (44.7) | | Perineal | 12 (70.6) | 31 (36.5) | | Planned stage procedure | 10 (58.8) | 21 (24.7) | |
| Orthoplasty | | | | Nesbit plication | 16 (94.1) | 72 (84.7) | | Mean number of Nesbit plications sutures | 1.25 | 1.32 | | Division of urethral plate | 10 (58.8) | 20 (23.5) | | Corporal body grafting | 2 (11.8) | 11 (12.9) | |
| Urethroplasty | | | | TIP | 6 (35.3) | 62 (73.8) | | Scrotal skin tube inlay/onlay | 6 (35.3) | 8 (9.5) | | Island inlay/onlay | 2 (11.8) | 3 (3.6) | | Flap inlay | 2 (11.8) | 3 (3.6) | | Combination distal TIP/island inlay | 1 (5.9) | 8 (9.5) | |
| Scrotoplasty | | | | Simple | 4 (25) | 31 (37.8) | | Complex | 12 (75) | 51 (62.2) | |
| Gonads | | | | UDT | 8 (47.1) | 12 (14.1) | | Gonad biopsy | 4 (23.5) | 0 (0.0) | | Gonadectomy | 6 (35.3) | 0 (0.0) | |
| Outcomes | | | | Mean total number of procedures | 2.06 | 1.61 | | Mean total number of procedures—planned procedures | 0.47 | 0.36 | | Patients with a complication | 5 (29.4) | 19 (22.4) | | Clinical follow-up (years) | 2.07 | 1.89 | |
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