The Effects of Chlormadinone Acetate on Lower Urinary Tract Symptoms and Erectile Functions of Patients with Benign Prostatic Hyperplasia: A Prospective Multicenter Clinical Study
Table 2
International prostate symptom scores.
(a)
Voiding scores
Incomplete emptying
Intermittency
Weak stream
Straining
Voiding subscore
Mean
SE
Mean
SE
Mean
SE
Mean
SE
Mean
SE
Week 0†
111
2.23
0.16
111
2.10
0.16
111
3.43
0.14
110
1.65
0.15
111
9.38
0.43
Week 8
93
1.56*
0.15
93
1.63*
0.15
93
2.52*
0.16
92
1.20*
0.14
93
6.92*
0.42
Week 16
86
1.32*
0.14
86
1.53*
0.17
86
2.27*
0.17
86
1.14*
0.14
86
6.27*
0.49
84
1.24*
0.13
84
1.42*
0.14
84
2.11*
0.16
84
0.99*
0.13
84
5.76*
0.41
81
1.37*
0.15
81
1.35*
0.14
81
2.07*
0.17
79
1.19*
0.15
81
5.92*
0.42
Week 48#
83
1.42*
0.13
83
1.66*
0.17
83
2.30*
0.16
82
1.28
0.15
83
6.63*
0.47
(b)
Storage scores
IPSS total score
IPSS-QOL score
Frequency
Urgency
Nocturia
Storage subscore
Mean
SE
Mean
SE
Mean
SE
Mean
SE
Mean
SE
Mean
SE
Week 0†
110
2.61
0.15
110
2.11
0.16
111
2.34
0.12
111
7.02
0.33
111
16.40
0.64
111
4.24
0.11
Week 8
93
2.24*
0.16
92
1.86
0.16
93
2.45
0.12
93
6.52
0.33
93
13.45*
0.63
93
3.58*
0.13
Week 16
86
1.73*
0.15
86
1.35*
0.15
86
2.45
0.12
86
5.56*
0.34
86
11.83*
0.72
86
3.20*
0.13
Week 24‡
84
1.65*
0.13
84
1.43*
0.14
84
2.06*
0.11
84
5.15*
0.31
84
10.91*
0.63
81
2.95*
0.14
81
1.72*
0.14
81
1.39*
0.15
81
2.15
0.13
81
5.28*
0.34
81
11.21*
0.67
81
3.09*
0.14
Week 48#
83
1.92*
0.15
81
1.40*
0.14
83
2.11
0.12
83
5.43*
0.31
83
12.06*
0.7
81
3.01*
0.15
Dunnett's multiple comparison test; P < 0.05; IPSS: International Prostate Symptom Score; QOL: quality of life; The day of the first dose; Week 8 of follow-up period; Week 16 of follow-up period; Week 32 of follow-up period.
