|
| References of cases | Treatment types | Follow-up duration | Complete remission | Partial remission | No response |
Total sex/age histology |
|
| Raderer et al. [11] | RCHOP or RCNOP
regime | 19 months mean
Range 10–45 | 20 (77%) | 6 (23%) | 0 | 26 patients with MALT lymphoma of bladder |
|
| Terasaki et al. [12] | Radiotherapy Gy 26 and Rituximab chemotherapy after remission | 14 months | 1 patient | | | 1 female aged 64 years with MALT lymphoma of bladder |
|
| Takahara et al. [13] | TURBT and Radiotherapy 40 Gy in 20 fractions | 3 monthly intervals to, duration is not available to author | 1 patient | | | 1 female aged 85 years with extranodal marginal zone B-cell lymphoma |
|
| Kakuta et al. [14] | Rituximab in combination with CHOPP chemotherapy after transurethral biopsy | Duration is not available to author | 1 patient | | | 1 female aged 84 years with extranodal marginal zone B-cell lymphoma of bladder |
|
|
Siegel and Napoli [15] | Extensive resection | Duration is not stated | Alive, but outcome with regard to response is not available to author | Alive, but outcome with regard to response is not available to author | | 1 elderly female with B-cell lymphoma of dome of bladder with signet ring cell component |
|
| Hayashi et al. [16] | 3 courses of R CHOPP chemotherapy | Duration is not available to author | 1 patient | | | 1 female age not available to author with DCBCL (primary diffuse large B-cell lymphoma of urinary bladder) |
|
| Abraham et al. [17] | Resectional biopsy and non-Hodgkin’s lymphoma therapy | Duration is not stated | 1 | | | 1 female aged 72 years with extranodal monocytoid B-cell lymphoma (MBCL) derived from marginal zone lymphocyte |
|
|
Sundaram and Zhang [18] | Resection but details of further management not available | Details is not available to author | | | |
1 female aged 67 years with localized Epstein-Barr virus (EBV) positive B-cell lymphoproliferative disorder (LPD)/polymorphous B-cell lymphoma of the bladder |
|
|
Oh and Zang [19] | Transurethral resection biopsy and two cycles of systemic cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOPP) chemotherapy | Duration is not stated | 1 patient with simultaneous restoration of urinary function | | | 1 male aged 35 years with diffuse large B-cell lymphoma (non-Hodgkin’s lymphoma) |
|
| Wang et al. [20] | TURBT and four cycles of CHOPP (cyclophosphamide, doxorubicin, vincristine, and prednisone) chemotherapy | 12 months | 1 with good response and remained in clinical remission for 12 months after treatment | | | 1 male aged 45 years with T-cell lymphoma of urinary bladder |
|
| Mourad et al. [21] | Transurethral resection biopsy of lesion and
CHOPP chemotherapy and he received cyclophosphamide, doxorubicin, vincristine, and prednisone | Duration not available to author: appeared case was reported earlier without details of long-term follow-up | Response not available | | | 1 male aged 52 years who had shistosomiasis and found to have T-cell lymphoma of urinary bladder which Mourad et al. [21] felt was induced by shistosomiasis |
|
|
Ando et al. [22] | Transurethral resection of bladder tumour only | 3 years | 1 | | | 1 female aged 77 years with primary low-grade B-cell lymphoma of the MALT type |
|
|
Simpson et al. [23] | Details not available to author | Details are not available to author | Details not available to author | — | — | 1 female with T-cell primary lymphoma of bladder and urethra |
|
| Mearini et al. [24] | Transurethral resection of bladder tumour (Burkitt’s lymphoma) plus subsequent antiretroviral treatment with stavudine (40 mg twice daily), lamivudine (150 mg twice daily), and nelfinavir (750 mg 3 times daily), as well as antitumour polychemotherapy (4 cycles of cyclophosphamide, vincristine, doxorubicin, and dexamethasone, alternated with 4 cycles of methotrexate and cytarabine) | 8 months of followup | Complete resolution and biopsy of small mucosal lesion at site of previous tumour 8 months later only showed fibrous tissue on immunohistochemical and histological examination | | | 27-year-old man with Burkitt’s lymphoma |
|
| Tsiriopoulos et al. [25] | Cystectomy and ileal conduit after failure of conservative treatment for presumed interstitial cystitis | Details are not available to author | Details are not available to author | Details are not available to author | Details are not available to author | 75-year-old patient with past history of chronic lymphatic leukaemia histology of bladder showed primary splenic marginal zone lymphoma simulating interstitial cystitis |
|
| Downs et al. [26] | Details are not available to author | Details are not available to author | Details are not available to author | Details are not available to author | Details are not available to author | They concluded that primary lymphoma of the bladder has a good prognosis and responds to a variety of therapeutic modalities |
|
| Simpson et al. [27] | 3 cases | 7 years.
39 months.
Details are not available to author | Alive and free of tumour.
Died after 39 months.
Details are not available to author | | | A 70-year-old man with low grade type
A 67-year-old woman with intermediate-grade type
76-year-old woman with lymphoma in the urethra |
|
|
Isaacson and Wright [28] | 2 cases, details are not available to author | Details are not available to author | Details are not available to author | Details are not available to author | Details are not available to author | Details are not available to author |
|
| Ohsawa et al. [10] | 3 cases, details are not available to author | Details are not available to author | Details are not available to author | Details are not available to author | Details are not available to author | Details are not available to author |
|
|
Sönmezer et al. [9] | Transurethral biopsy, partial cystectomy, total hysterectomy, bilateral oophorectomy, and four courses of CHOP regimen (cyclophosphamide, vincristine, doxorubicin, and prednisolone) | 6 years | Alive and well with no local recurrence of distant metastasis | | | 1 female aged 50 years with high-grade B-cell lymphoma |
|
| Kuhara et al. [8] | | Details of duration of followup are not available to author | Outcome is not available to author | Outcome is not available to author | | Diffuse B-cell lymphoma of medium-sized cell |
|
| Sufrin et al. [7] | 13% of 599 patients with malignant lymphoma had secondary bladder involvement and were treated with local radiotherapy | 1952 to 1972 | Good response | | | 13% of 599 patients with secondary bladder lymphoma (details of the various types are not available to author) |
|
|
Cohen et al. [6] | Details of case are not available to author | Details of case are not available to author | Details of case are not available to author | Details of case are not available to author | Details of case are not available to author | 1 case of primary B-cell lymphoma of bladder |
|
| Zukerberg et al. [5] | 5 cases (diagnosis of malignant lymphoma was excluded in 1 leaving 4 as lymphoma of T-cell type
Of 2 muscle invasive tumours,
2 cases were too recent to have followup | 4
Too recent for followup
| 1 alive with no tumour after 4 years following radiotherapy. and chemotherapy.
Details are not available to author | | | |
|
| Al-Maghrabi et al. [4] | Radiotherapy (35 Gy) | 13 years,
5 years,
3 years,
2 years,
respectively | Alive no recurrence.
Alive no recurrence.
Alive no recurrence.
Alive with no disease | | | 64-year-old female,stage IAE
69-year-old female, low-grade MALT lymphoma, stage IAE
72-year-old female, low-grade lymphoma of MALT type-stage IAE
62-years-old male, B-cell malignant lymphoma of MALT type-stage IAE |
|
| Mantzarides et al. [29] | Details of treatment are not available to author | Further details are not available to author | Further details are not available to author | Further details are not available to author | Further details are not available to author | 82-year-old female with primary diffuse large B-cell lymphoma of the bladder wall |
|
|
Evans and Moore [30] | Transurethral biopsy of bladder tumour and she received a course of R-CHOP (cyclophosphamide, doxorubicin, vincristine, prednisolone, and rituximab) chemotherapy | 4 months | | CT scan showed regression of lesion and symptomatic improvement | | 64-year-old female with histologically proven diffuse large B-Cell non-Hodgkin’s lymphoma (primary) |
|
| Arda et al. [31] | Open biopsy; she refused surgical operation and was referred to oncologist for chemotherapy | Further details are not available to author | Further details are not available to author | Further details are not available to author | Further details are not available to author | 54-year-old female had open biopsy proven to be malignant non-Hodgkin’s lymphoma |
|
|
Aceñero, et al. [32] | Details are not available to author | Details are not available to author | Details are not available to author | Details are not available to author | Details are not available to author | 3 cases of primary malignant lymphoma of urinary bladder (2 of high grade) of MALT type |
|
|
Jacobs and Symington [33] | Cystectomy | 3 years | Alive and well with no recurrence of locally or distant metastasis | | | 61-year-old woman with primary lymphoma of urinary bladder |
|
Diaz-Peromingo et al. [34]
| TUR biopsies and CNOP (cyclophosphamide, mitoxantrone, vincristine, and prednisolone) and monoclonal antibodies anti-CD20 | Short period of follow-up case reported shortly after initial treatment | Good initial response | | | 79-year-old man tumour B-cell lymphoma (non-Hodgkin’s) which was initially thought to be primary; however, PER scan confirmed that it was a secondary bladder lymphoma |
|
| Rijo et al. [35] | Open per vaginal partial excision of paraurerethal lesion. extending to the trigone of the bladder (this was a paraurethal lesion not a bladder lesion).
Six cycles of immunochemotherapy: anti-CD20 (Rituximab) combined with chemotherapy (high doses of methotrexate and cytarabine with conventional cystostatics and prophylactic administration of G-CSF after chemotherapy cycles).
After the completion of the third cycle of treatment, the patient achieved near-complete remission as well as a nearly complete regression of the paraurethral tumour and the lesion of the 5th lumbar vertebra. Haematological grade 2 toxicity and gastrointestinal grade 1 toxicity were reported
| 9 months | 1 | | | 1 female aged 27 years
|
|
| Hatano et al. [36] | Transurethral resection of bladder tumour and left total nephroureterectomy; histology adenocarcinoma G2pT2 in renal pelvis and MALT-type lymphoma of bladder; radiotherapy 36 Gy to bladder | 14 months | Alive with no evidence of recurrence | | | 84-year-old with MALT-type lymphoma of bladder and adenocarcinoma of left renal pelvis |
|
