Review Article

Recent Pathophysiological Aspects of Peyronie’s Disease: Role of Free Radicals, Rationale, and Therapeutic Implications for Antioxidant Treatment—Literature Review

Table 1

Chemical reactions during oxidative stress and direct reactions of vitamin E and coenzyme Q10 with reactive species.

Superoxide anion

Hydrogen peroxide SOD

Hydroxyl radical ()
(Fenton’s reaction)

Hydroxyl radical ()
(Haber-Weiss reaction)

Hypochlorous acid (HOCl)MPO

Singlet oxygen ()

Nitric oxide ()NOS

Peroxynitrite ()

Peroxynitrous acid (HOONO)

Hydroxyl radical () and nitrogen dioxide radical ()

Antioxidant activity of vitamin E(α-tocopherol-OH)

Antioxidant activity of coenzyme Q10