Efficacy of Transdermal Oxybutynin in the Treatment of Overactive Bladder Syndrome: Does It Make Sense Using It in 2017?

Table 3

Changes 3D from baseline in the 3 DVD tool at 12 months of treatment with OXY-TDS (naive/nonnaive patients).

3 DVD	Naive (); mean (SD)	Nonnaive (); mean (SD)	Diff (95% CI)	value
DUF (episodes/day)	7.07 (1.8)	6.9 (1.5)	0.4 (−0.7; 1.3)	0.341
NUF (episodes/night)	0.87 (0.7)	0.7 (0.8)	0.0 (−3.0; 0.7)	0.411
UF/24 hours (episodes/day)	8.0 (2.1)	7.6 (1.7)	6.3 (−0.4; 1.7)	0.298
Maximum UV (ml)	444.6 (486.1)	302.1 (83.1)	24.1 (−41.7; 100.0)	0.461
Nocturnal UV (ml)	112.6 (84.9)	143.83 (168.9)	−31.2 (−135.9; 73.5)	0.550
Mean UV (ml)	205.5 (54.9)	191.0 (NA)	14.5 (−180.6; 209.6)	0.828
Urgency (episodes/day)	1.5 (2.1)	1.5 (1.2)	0.5 (−0.9; 1.0)	0.892
Urgency grade	1.8 (1.3)	2.5 (1.3)	−0.7 (−1.3; 0.0)	0.071
UUI (episodes/day)	0.2 (0.5)	0.6 (1.0)	0.0 (−0.3; 0.0)	0.328
SUI (episodes/day)	0.0 (0.0)	0.2 (0.6)	0.0 (0.0; 0.0)	0.110
Pad/underwear changes (number/day)	0.6 (1.0)	0.8 (1.1)	0.0 (−0.6; 0.0)	0.044
Liquid intake/24 h (ml)	1484.73 (613.5)	1439.0 (481.9)	45.7 (−326.4; 417.1)	0.805
Urine output/24 h (ml)	1609.17 (446.6)	1457.89 (347.2)	151.3 (−115.5; 418.0)	0.258
Nocturnal urine output (ml)	167.77 (138.3)	185.26 (228.2)	−17.5 (−162.6; 127.6)	0.808

3 DVD: 3-day voiding diary; DUF: daytime urinary frequency; NUF: night-time urinary frequency; SD: standard deviation; SUI: stress urinary incontinence; UF/24 h: 24-hour urinary frequency (total number of episodes/24 hours); UUI: urge urinary incontinence. values: Student’s t-test or Wilcoxon signed rank test. Change: mean difference, or Hodges-Lehman estimator of location shift.