Review Article

Adjuvant Therapy for Stage IB Germ Cell Tumors: One versus Two Cycles of BEP

Table 1

Toxicities of BEP chemotherapy.

Dose-related toxicities of BEPNon dose relatedUnknown relationship to dose

InfertilityFebrile neutropeniaSecond malignancy
Peripheral neuropathyAlopeciaCardiovascular disease
OtotoxicityNausea/vomiting
Raynaud’s phenomena
Fatigue
Skin toxicity
Avascular necrosis hip
Pneumonitis/lung fibrosis
Renal damage
Anaemia
Metabolic syndrome