Histoprotective Effect of Essential Oil from Citrus aurantifolia in Testosterone-Induced Benign Prostatic Hyperplasia Rat

Figure 4

Photomicrographs of prostate glands of experimental groups after 21 days of treatment: (a) model; (b) low dose of oil (30 mg/kg); (c) mid-dose of oil (100 mg/kg); (d) high dose of oil (300 mg/kg); (e) finasteride (15 mg/kg); (f) normal control. Prostatic secretions (S), epithelium (EP), and fibromuscular stroma (FS), model group had larger acini with thicker epithelium, more prostatic secretions, and thinner fibromuscular stroma. Low dose group had slightly large acini, light prostatic secretions and thin fibromuscular stroma. Mid-dose group shows smaller acini with thinner epithelium, moderate prostatic secretion, thick strand of the fibromuscular stroma. High-dose group shows small-sized acini, moderate prostatic secretions, thin epithelium and thick fibromuscular stroma. Finasteride group had almost absent prostatic secretions and a very few amount of fibromuscular stroma, sham group had small-sized acini, little or no prostatic secretion, together with few strands of the fibromuscular stroma.

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