Review Article

CK20 and CK5/6 Immunohistochemical Staining of Urothelial Neoplasms: A Perspective

Figure 6

(a) High-grade urothelial carcinoma with focal squamous differentiation. (b) Immunohistochemical staining demonstrating strong CK5/6 staining in the area of squamous differentiation. The remaining part of carcinoma stains for CK20. (c) High-grade urothelial carcinoma with basosquamous morphologic features. (d) Immunohistochemical staining in basosquamous carcinoma featuring strong immunostaining for CK5/6 and complete absence of CK20 positivity.
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