Research Article

High-Intensity Focused Ultrasound (HIFU) Focal Therapy for Localized Prostate Cancer with MRI-US Fusion Platform

Table 1

Baseline characteristics of the patients.

Characteristics

Mean age (years) ± SD68.4 ± 5.9
Mean BMI (kg/m2) ± SD23.8 ± 3.0
PSA
 <4 ng/mL (n)1 (5%)
 4–10 ng/mL (n)13 (65%)
 >10–20 ng/mL (n)6 (30%)
Mode of diagnosis
 MRI-USG fusion target + systematic biopsy (n)14 (70%)
 Mapping transperineal systematic biopsy (n)6 (30%)
Number of index lesions per HIFU surgery
 1 (n)18 (90%)
 2 (n)2 (10%)
Characteristics of index lesions under treatment on MRI
 Visible on MRI (n)22 (100%)
 PI-RADS 3 (n)1 (5%)
 PI-RADS 4 (n)14 (70%)
 PI-RADS 5 (n)5 (25%)
ISUP grade group of index lesions under treatment
 Grade group 1 (n)12 (54.5%)
 Grade group 2 (n)5 (22.7%)
 Grade group 3 (n)3 (13.6%)
 Grade group 4 (n)2 (9.1%)
 Grade group 5 (n)0
Index lesion location
 Peripheral zone (n)18 (81.8%)
 Transitional zone (n)4 (18.2%)
 Apex (n)5 (22.7%)
 Middle (n)9 (40.9%)
 Base (n)8 (36.4%)
Mean distance between the lesion from rectum (mm)15.7 ± 8.3
Mean index lesion size (cm3) ± SD0.89 ± 0.95

SD, standard deviation; BMI, body mass index; PSA, prostatic specific antigen.