Review Article
Novel Roles of the Picornaviral 3D Polymerase in Viral Pathogenesis
Table 1
Amino acid sequence alignment of 3Dpol from five different picornaviruses to TMEV 3Dpol (Swiss Prot Accession: P13899) which was used for the query sequence. The sequence alignment was run using Blastp from National Center for Biotechnology Information (NCBI) web site for 2 or more sequences [6, 7]. Column heading definitions: Accession = the accession # from the Swiss Prot database of the aligned sequence. Identities = percentage of amino acids that are identical to the query in the alignment. Positives = the percentage of amino acid that have similar physical properties to the query in the alignment. Gaps = percentage of amino acids that create a gap to the query in the alignment. Score = Bit score. This is derived from the raw alignment score in which the statistical properties of the scoring system used have been taken into account. Because bit scores have been normalized with respect to the scoring system, they are used to compare alignment scores from different searches. value = Expectation value. The number of different alignments with scores equivalent to or better than this alignment that are expected to occur in a database search by chance. Hence, the lower the value, the more significant the score.
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