Table of Contents Author Guidelines Submit a Manuscript
Advances in Virology
Volume 2011, Article ID 650930, 6 pages
http://dx.doi.org/10.1155/2011/650930
Research Article

The Prevalence of STIV c92-Like Proteins in Acidic Thermal Environments

1Department of Plant Sciences and Plant Pathology, Montana State University, Bozeman, MT 59717, USA
2Thermal Biology Institute, Montana State University, Bozeman, MT 59717, USA
3Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA

Received 26 March 2011; Accepted 23 May 2011

Academic Editor: Claude Krummenacher

Copyright © 2011 Jamie C. Snyder et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A new type of viral-induced lysis system has recently been discovered for two unrelated archaeal viruses, STIV and SIRV2. Prior to the lysis of the infected host cell, unique pyramid-like lysis structures are formed on the cell surface by the protrusion of the underlying cell membrane through the overlying external S-layer. It is through these pyramid structures that assembled virions are released during lysis. The STIV viral protein c92 is responsible for the formation of these lysis structures. We searched for c92-like proteins in viral sequences present in multiple viral and cellular metagenomic libraries from Yellowstone National Park acidic hot spring environments. Phylogenetic analysis of these proteins demonstrates that, although c92-like proteins are detected in these environments, some are quite divergent and may represent new viral families. We hypothesize that this new viral lysis system is common within diverse archaeal viral populations found within acidic hot springs.