Bacterial Toxin Fusion Proteins Elicit Mucosal Immunity against a Foot-and-Mouth Disease Virus Antigen When Administered Intranasally to Guinea Pigs
Figure 4
Enumeration of IgG and IgA antibody-secreting cells. Spleen and nasal mucosae were collected from 3 of 6 animals from each group at the conclusion of the study, and lymphocytes were collected from these tissues to enumerate IgG (a) and IgA (b) antibody-secreting cells by ELISPOT. Y-axis represents number of ASC per million cells collected.