Research Article
No Evidence of XMRV or MuLV Sequences in Prostate Cancer, Diffuse Large B-Cell Lymphoma, or the UK Blood Donor Population
(a) Amplification from fresh and FFPE tissues by nested PCR |
| | Fresh prostate tissue | Japan samples | Indian samples | LCBCL samples |
| Number of cancerous samples | 16/55 | 16 | 10/20 | 10 | Number of noncancerous samples (unknown status) | 18/55 (21/55) | 0 | 10/20 | 0 | Mean age (range) | unknown | unknown | 72 (62–85) | 43 (27–83) | Beta globin + | 55/55 | 16/16 | 20/20 | 10/10 | XMRV + | 0 | 0 | 2/20 | 0 | MuLV + | 0 | 0 | 4/20 | 0 | IAP + | 0 | 0 | 5/20 | 0 | mtDNA + | nd | nd | 2/10 | nd |
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(b) Specific PCR results from Indian samples |
| Indian sample number | Cancer status | PCR result using specific primers | β-globin | IAP | mtDNA | MLV gag | XMRV LTR |
| 6489c/10 | cancer | + | + | + | + | + | 5383c/10 | cancer | + | + | − | + | + | 5406a3/10 | cancer | + | + | − | − | − | 2896c/10 | BPH | + | + | + | + | − | 5349c/10 | cancer | + | + | − | + | − |
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