Research Article

No Evidence of XMRV or MuLV Sequences in Prostate Cancer, Diffuse Large B-Cell Lymphoma, or the UK Blood Donor Population

Table 2

(a) Amplification from fresh and FFPE tissues by nested PCR

Fresh prostate tissueJapan samplesIndian samplesLCBCL samples

Number of cancerous samples16/551610/2010
Number of noncancerous samples (unknown status)18/55 (21/55)010/200
Mean age (range)unknownunknown72 (62–85)43 (27–83)
Beta globin +55/5516/1620/2010/10
XMRV +002/200
MuLV +004/200
IAP +005/200
mtDNA +ndnd2/10nd

(b) Specific PCR results from Indian samples

Indian sample numberCancer statusPCR result using specific primers
β-globinIAPmtDNAMLV gag XMRV LTR

6489c/10cancer+++++
5383c/10cancer++++
5406a3/10cancer++
2896c/10BPH++++
5349c/10cancer+++