Research Article

Failure to Detect XMRV-Specific Antibodies in the Plasma of CFS Patients Using Highly Sensitive Chemiluminescence Immunoassays

Table 1

Results summary for XMRV positive PCR samples. All samples that tested positive for XMRV gag sequence in original study [17], as well as the two samples that reacted with the gp70 CMIA, are displayed. Bolded samples showed the VP42 gag sequence but did not react with the CMIAs. The italic data shows the two samples that were reactive in the gp70 CMIA. CMIA values less than one are considered nonreactive. XMRV GAG: Nested gag PCR. Mcox: murine mitochondrial cytochrome oxidase qPCR. IAP: Intracisternal A-type particle PCR.

InitialInitialRepeat
PCR resultstesttesttest
XMRVp15Egp70gp70 
IDUnblinded IDGAGMcoxIAPS/COS/COS/CO

72TH72.1+++0.380.06
128TH04.1+++0.160.07
129TH01.7+++0.150.06
131TH01.8++0.120.06
132TH01.3+++0.150.06
134TH06.1+++0.150.07
135TH01.1+++0.140.09
136TH05.1+++0.160.06
137TH07.1+++0.167.777.17, 7.21
138TH07.20.149.028.65, 8.77
143TH10.1+++0.140.07
144TH11.1++0.140.06
147TH02.1+++0.140.07
152TH01.5+++0.130.07
153TH21.1+++0.150.07
155TH20.1+++0.160.06
156TH02.2+++0.170.07
158TH08.1+++0.130.07
160TH03.1+++0.130.07
161TH12.1+++0.110.06
163TH19.1+++0.160.720.75, 0.72
164TH16.1+++0.150.07