Naturally Occurring Polymorphisms of the Mouse Gammaretrovirus Receptors CAT-1 and XPR1 Alter Virus Tropism and Pathogenicity

<table>Phylogenetic tree of the Env genes of E-MLV gammaretroviruses.  The tree includes laboratory mouse isolates FrMLV, MoMLV, and Rauscher MLV (RaMLV), the naturally occurring viruses AKV MLV, CasBrE, and HoMLV, and the Env gene of the <i>Fv4</i> restriction gene.  The three related groups are bracketed.  Sequences from GenBank were aligned using ClustalW2 and used to generate neighbour-joining trees.  The X-MLV NZB-9-1 was included to root the tree.</table>

Advances in Virology

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Figure 3

Figure 3: Naturally Occurring Polymorphisms of the Mouse Gammaretrovirus Receptors CAT-1 and XPR1 Alter Virus Tropism and Pathogenicity 