Advances in Virus-Directed Therapeutics against Epstein-Barr Virus-Associated Malignancies
Figure 3
Effect of HDACi and GCV combination treatment on other EBV-positive lymphoma cells. (a) Effect of combination treatment on the BL line Daudi. Four hundred thousand cells per ml per well were cultured with 60 μM GCV in the appropriate wells. Assay parameters were as described in the legend to Figure 2. (b) Effect of combination treatment on the EBV-transformed lymphoblastoid cell line JY. In this case, 200,000 cells per well were plated in the presence of 60 μM GCV, or vehicle, as indicated. Experiments were repeated a minimum of three times and error bars represent standard deviation.
