Orthopoxvirus Genes That Mediate Disease Virulence and Host Tropism
Table 2
Orthopoxviral ankyrin-F-box-like proteins.
VACV-COP
CPXV-GRI
MPXV-ZAI
VARV-IND
ORF
Size, aa
ORF
Size, aa
ORF
Size, aa
ORF
Size, aa
C19L*
259
D3L
*
586
J3L
*
587
None
None
C17L*
386
D4L
*
672
None
None
None
None
None
None
D8L
661
None
None
None
None
None
None
D14L
764
None
None
None
None
None
None
C1L
437
D1L
*
437
None
None
None
None
C3L
833
None
None
None
None
None
None
C9L
668
D7L
660
D6L
452
C9L
634
C11L
614
D9L
630
D7L
153
M1L
472
O1L
474
O1L
442
O1L
446
K1L
284
M1L
284
C1L
284
C1L
66
B4R
558
B3R
558
B5R
561
B6R
558
B18R
574
B16R
574
None
None
B19R
574
B20R
127
B18R
795
B17R
793
B21R
787
B21R*
91
K1R
581
None
None
None
None
None
None
None
None
N4R
*
437
None
None
B23R*
386
H2R
*
672
None
None
None
None
B25R*
259
H3R
*
586
J1R
*
587
G1R
585
Asterisks denote ORFs that are duplicated in left and right inverted terminal repeat regions of the viral genome. ORFs with full length are set in bold. The ORFs for the proteins with experimentally confirmed interaction with the cellular Cullin1-containing ubiquitin-protein ligase are indicated by bold italic letters.
