Orthopoxvirus Genes That Mediate Disease Virulence and Host Tropism

Table 3

Orthopoxviral BTB-kelch-like proteins.

VACV-COP		CPXV-GRI		MPXV-ZAI		VARV-IND
ORF	Size, aa	ORF	Size, aa	ORF	Size, aa	ORF	Size, aa
None	None	D11L	521	None	None	None	None
C2L	512	C18L	512	D18L	107	None	None
F3L	480	G3L	485	C9L	487	C7L	179
A55R	564	A57R	564	None	None	J7R	71
B10R	166	B9R	501	None	None	None	None
None	None	B19R	557	B18R	70	B22R	70

ORFs with full length are set in bold. The ORFs for the proteins with experimentally confirmed interaction with the cellular Cullin 3-containing ubiquitin-protein ligase are indicated by bold italic letters.