Elucidating the Interacting Domains of Chandipura Virus Nucleocapsid Protein

Table 2

Cumulative results of CHPV N protein fragments interaction analysis.

Protein pair used for interaction analysis	Interaction analysis by ZDOCK and RDOCK	Y2H assay		ELISA	Known from the Literature
		HIS3 reporter (nutritional selection)	MEL1 reporter (α-galactosidase assay)
N1-N	√	√	√	√	√ [12]
N1-P	√	√	√	√	√ [13]
N1-M	√	√	√	√	—
N1-G	X	√	√	√	—
N2-N	√	√	√	√	√ [12]
N2-P	√	X	X	X
N2-M	X	X	X	X	—
N2-G	√	√	√	√	—
N3-N	√	√	√	√	√ [12]
N3-P	√	√	√	√	√ [13]
N3-M	√	√	√	√	—
N3-G	√	X	X	X	—

√ represents positive interaction.
X represents negative interaction.