Structural Differences Observed in Arboviruses of the Alphavirus and Flavivirus Genera
Figure 13
Thin-section electron microscopy of Sindbis virus-cell complexes at pH 7.2. A panel of images obtained by TEM illustrates two representative populations of particles at different incubation temperatures. High-magnification images show examples of electron-dense full particles at the cell surface at 4°C (row (a)) and empty particles with loss of RNA electron density predominantly at 37°C (row (b)). In row (b), middle panel, there is indication of a stalk connecting the virus and the cell (arrow). Bars, 50 nm. From Vancini et al. 2013 [133].
