Research Article

Immunogenicity of RSV F DNA Vaccine in BALB/c Mice

Table 2

Th2/Th1 (IgG1/IgG2a < 1 and IgG2b/IgG2a < 1) antibody ratios. IgG isotypes were detected by ELISA from serum samples of BALB/c mice (RSV-infected and PF DNA-immunized) on day 49. Data is presented as an average of triplicates performed twice.

ā€‰IgG1/IgG2aIgG2b/IgG2a
ā€‰RSVPF DNARSVPF DNA

Day 140.1680.6790.9110.850
Day 280.5530.4430.8270.666
Day 490.3920.2360.7670.819