Phage-Displayed Peptides Selected to Bind Envelope Glycoprotein Show Antiviral Activity against Dengue Virus Serotype 2

Figure 4

Peptide sequences resulting from binder phages confirmed by phage-ELISA. (a) Peptides resulting from panning on full DENV2 envelope. (b) Peptides resulting from panning on recombinant DENV2 envelope domain III. Sequence logos and consensus sequence, as calculated using JalView, are depicted below each list of peptides. Coloring of residues and sequence logos as per Zappo scheme, where residues are colored according to their physicochemical properties as follows: pink, aliphatic/hydrophobic; orange, aromatic; red, positive; green, negative; blue, hydrophilic; magenta, proline/glycine; and yellow, cysteine.

(a)

(b)