Adaptation and Molecular Characterization of Two Malaysian Very Virulent Infectious Bursal Disease Virus Isolates Adapted in BGM-70 Cell Line
(a) A normal confluent monolayer of BGM-70 cells compared with (b) UPM0081, BGMP5 induced CPE on BGM-70 infected cells including small refractive cells, cytoplasmic granulation, cell rounding, and detachment at 6 days pi. (c) BGM-70 cells infected with UPM0081 at BGMP18 and (d) UPM190 BGMP19 at days 9 and 8, respectively, showing little CPE compared with (e) uninfected controls at day 5 and (f) at day 7. Bar = 100 µm.
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