Comparison of the Immunogenicity and Safety of Two Pediatric TBE Vaccines Based on the Far Eastern and European Virus Subtypes

Table 2

Adverse reactions after vaccination with Tick-E-Vac or FSME-IMMUN Junior.

Schedule	Tick-E-Vac			FSME-IMMUN Junior
	N	n	%	N	n	%
	After the first dose administered
Conventional	49	10	20.4	42	11	26.2
Rapid	27	6	22.2	28	5	17.9
In total for the two schedules	76	16^a	21.1	70	16^b	22.9
	After the second dose administered
Conventional	49	6	12.2	42	7	16.7
Rapid	27	1	3.7	28	1	3.6
In total for the two schedules	76	7^a	9.2	70	8^b	11.4
	In total after both doses of vaccine administered
Conventional	49	11	22.4	42	12	28.6
Rapid	27	7	25.9	28	5	17.9
In total for the two schedules	76	18	23.7	70	17	24.3

N—total number of subjects; n—number of subjects who developed the adverse reactions. ^a,bStatistically significant differences of reverse reactions after the first injection and after the second one (CST).