Research Article
Association of Septic Shock with Mortality in Hospitalized COVID-19 Patients in Wuhan, China
Table 1
Demographics and clinical outcomes in patients with COVID-19.
| | | All patients | Clinical outcomes | value | | Septic shock | Nonseptic shock | | 212 | 30 | 182 |
| | Characteristic | | | | | | Age (years)—median (IQR) | 62 (53–70) | 73.5 (59–84) | 61 (51.25–68) | <0.001 | | Age (years)—No. (%) | | | | 0.019 | | 20–40 | 17/212 (8) | 2/30 (6.7) | 15/182 (8.2) | 1.000 | | 41–65 | 114/212 (53.8) | 9/30 (30) | 105/182 (57.7) | 0.005 | | ≥65 | 88/212 (41.5) | 19/30 (63.3) | 69/182 (37.9) | 0.009 | | Sex—No. (%) | | | | 0.914 | | Male | 115/212 (54.2) | 16/30 (53.3) | 99/182 (54.4) | | | Female | 97/212 (45.8) | 14/30 (46.7) | 83/182 (45.6) | | | Occupation—No. (%) | | | | ≤0.001 | | Employee | 57/212 (26.9) | 2/30 (6.7) | 55/182 (30.2) | 0.007 | | Self-employed | 8/212 (3.8) | 0/30 (0) | 8/182 (4.4) | 0.382 | | Retired | 96/212 (45.3) | 24/30 (80) | 72/182 (39.6) | <0.001 | | Unemployment | 51/212 (24.1) | 4/30 (13.3) | 47/182 (25.8) | 0.175 | | Medical staff—No. (%) | 5/212 (2.4) | 0/30 (0) | 5/182 (2.7) | 0.606 | | Disease status | | | | | | Mild | 74/212 (34.9) | 1/30 (3.3) | 73/182 (40.1) | <0.001 | | Severe | 117/212 (55.1) | 11/30 (36.6) | 106/182 (58.2) | 0.030 | | Critical | 22/212 (10.3) | 18/30 (60) | 4/182 (2.1) | <0.001 | | BMI-median—No. (%) | | | | 0.008 | | <25 | 150/212 (70.8) | 20/29 (69) | 130/166 (78.3) | 0.270 | | 25–30 | 36/212 (17) | 4/29 (13.8) | 32/166 (19.3) | 0.606 | | >30 | 9/212 (4.2) | 5/29 (17.2) | 4/166 (2.4) | 0.003 | | Temperature (°C)—No. (%) | | | | 0.003 | | ≤37.00 | 95/212 (44.8) | 5/30 (16.7) | 90/182 (49.5) | 0.001 | | 37.01–38.00 | 62/212 (29.2) | 12/30 (40) | 50/182 (27.5) | 0.162 | | 38.01–39.00 | 45/212 (21.2) | 9/30 (30) | 36/182 (19.8) | 0.205 | | ≥39.01 | 10/212 (4.7) | 4/30 (13.3) | 6/182 (3.3) | 0.038 | | Hypnotics—No. (%) | | | | <0.001 | | Yes | 68/212 (32.1) | 2/30 (6.7) | 66/153 (43.1) | <0.001 | | No | 115/212 (54.2) | 28/30 (93.3) | 87/153 (56.9) | 0.001 | | Smoking history—No. (%) | 30/212 (14.2) | 8/30 (26.7) | 22/182 (12.1) | 0.034 | | Drinking—No. (%) | 24/212 (11.3) | 5/30 (16.7) | 19/182 (10.4) | 0.373 | | Signs and symptoms—No. (%) | | | | | | Fever | 181/212 (85.4) | 21/30 (70) | 160/182 (87.9) | 0.010 | | Cough | 106/212 (50) | 16/30 (53.3) | 90/182 (49.5) | 0.694 | | Fever and cough | 177/212 (83.5) | 16/30 (53.3) | 161/182 (88.5) | <0.001 | | Chest distress | 2/212 (0.9) | 2/30 (6.7) | 0/182 (0) | 0.019 | | Nausea and vomiting | 1/212 (0.5) | 1/30 (3.3) | 0/182 (0) | 0.144 | | Dyspneic | 10/212 (4.7) | 1/30 (3.3) | 9/182 (4.9) | 1.000 | | Chronic medical illness/coexisting conditions—No. (%) | | | | | | Cirrhosis | 4/212 (1.9) | 2/30 (6.7) | 2/182 (1.1) | 0.105 | | Hypertension | 76/212 (35.8) | 14/30 (46.7) | 62/182 (34.1) | 0.182 | | Diabetes | 38/212 (17.9) | 12/30 (40) | 26/182 (14.3) | 0.001 | | Malignancy | 3/212 (1.4) | 2/30 (6.7) | 1/182 (0.5) | 0.055 | | Cerebrovascular disease | 6/212 (2.8) | 0/30 (0) | 6/182 (3.3) | 0.586 | | Chronic obstructive pulmonary disease | 5/212 (2.4) | 0/30 (0) | 5/182 (2.7) | 0.592 | | Chronic kidney disease | 6/212 (2.8) | 0/30 (0) | 6/182 (3.3) | 0.607 | | Chronic liver disease | 2/212 (0.9) | 0/30 (0) | 2/182 (1.1) | 1.000 | | Cardiovascular and cerebrovascular diseases | 30/212 (14.2) | 9/30 (30) | 21/182 (11.5) | 0.007 | | Digestive system disease | 16/212 (7.5) | 6/30 (20) | 10/182 (5.5) | 0.005 | | Endocrine system disease | 12/212 (5.7) | 1/30 (3.3) | 11/182 (6) | 0.698 | | Nervous system disease | 6/212 (2.8) | 2/30 (6.7) | 4/182 (2.2) | 0.200 | | Respiratory system disease | 18/212 (8.5) | 6/30 (20) | 12/182 (6.6) | 0.015 |
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