Research Article
Association of Septic Shock with Mortality in Hospitalized COVID-19 Patients in Wuhan, China
Table 2
Radiographic and laboratory findings of patients with COVID-19.
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Radiologic and laboratory findings | All patients | Clinical outcomes | value | | Septic shock | Nonseptic shock | | 212 | 30 | 182 |
| | Radiologic findings | | | | | | Abnormalities on chest CT—No./total No. (%) | | | | | | Combination of patchy ground-glass opacity and pulmonary consolidation | 39/212 (18.4) | 1/30 (3.3) | 38/182 (20.9) | 0.019 | | Crazy paving sign | 19/212 (9) | 6/30 (20) | 13/182 (7.1) | 0.022 | | Bilateral pulmonary multiple consideration and intralobular interstitial thickening | 7/212 (3.3) | 6/30 (20) | 1/182 (0.5) | <0.001 | | Laboratory findings | | | | | | White blood cell count, × 109/L | | | | ≤0.001 | | <4 | 54/212 (25.5) | 5/29 (17.2) | 49/176 (27.8) | 0.263 | | 4–10 | 133/212 (62.7) | 14/29 (48.3) | 119/176 (67.6) | 0.043 | | >10 | 18/212 (8.5) | 10/29 (34.5) | 8/176 (4.5) | <0.001 | | Neutrophil count, × 109/L | | | | 0.005 | | <40 | 52/212 (24.5) | 5/29 (17.2) | 47/176 (26.7) | 0.369 | | 40–75 | 77/212 (36.3) | 5/29 (17.2) | 72/176 (40.9) | 0.013 | | >75 | 76/212 (35.8) | 19/29 (65.5) | 57/176 (32.4) | 0.001 | | Lymphocyte count, × 109/L | | | | 0.066 | | <20 | 133/212 (62.7) | 25/29 (86.2) | 108/176 (61.4) | 0.008 | | 20–50 | 71/212 (33.5) | 4/29 (13.8) | 67/176 (38.1) | 0.007 | | >50 | 1/212 (0.5) | 0/29 (0) | 1/176 (0.6) | 1.000 | | Monocyte count, × 109/L | | | | 0.635 | | <3 | 78/212 (36.8) | 12/29 (41.4) | 66/175 (37.7) | 0.707 | | 3–10 | 101/212 (47.6) | 15/29 (51.7) | 86/175 (49.1) | 0.797 | | >10 | 25/212 (11.8) | 2/29 (6.9) | 23/175 (13.1) | 0.411 | | Platelet count, × 109/L | | | | 0.009 | | <100 | 12/212 (5.7) | 5/29 (17.2) | 7/175 (4) | 0.018 | | 100–300 | 152/212 (71.7) | 22/29 (75.9) | 130/175 (74.3) | 0.857 | | >300 | 40/212 (18.9) | 2/29 (6.9) | 38/175 (21.7) | 0.063 | | Activated partial thromboplastin time, s | 28.8 (23–39.25) | 34.55 (27.1–41.825) | 27.7 (20.3–38.8) | <0.001 | | Creatine kinase—CMB, U/L | 23.9 (21.65–25.1) | 23.6 (21.2–24.7) | 41.4 (24.2–45.6) | <0.001 | | Lactate, mmol/L | 1.2 (1.2–1.3) | 1.2 (1.2–1.3) | 2.1 (1.8–2.1) | <0.001 | | Alanine aminotransferase, U/L | | | | 0.023 | | <7 | 36/212 (17) | 0/29 (0) | 36/177 (20.3) | 0.006 | | 7–40 | 125/212 (59) | 20/29 (69) | 105/177 (59.3) | 0.324 | | >40 | 45/212 (21.2) | 9/29 (31) | 36/177 (20.3) | 0.196 | | Aspartate aminotransferase, U/L | | | | 0.008 | | <13 | 40/212 (18.9) | 1/29 (3.4) | 39/178 (21.9) | 0.024 | | 13–35 | 101/212 (47.6) | 12/29 (41.4) | 89/178 (50) | 0.389 | | >35 | 66/212 (31.1) | 16/29 (55.2) | 50/178 (28.1) | 0.004 | | Blood urea nitrogen, mmol/L | | | | 0.040 | | <3 | 28/212 (13.2) | 2/29 (6.9) | 26/176 (14.8) | 0.397 | | 3–8 | 117/212 (55.2) | 13/29 (44.8) | 104/176 (59.1) | 0.150 | | >8 | 60/212 (28.3) | 14/29 (48.3) | 46/176 (26.1) | 0.015 | | Creatinine, μmol/L | | | | 0.030 | | <88 | 170/212 (80.2) | 19/29 (65.5) | 151/177 (85.3) | 0.009 | | 88–144 | 31/212 (14.6) | 8/29 (27.6) | 23/177 (13) | 0.042 | | >144 | 5/212 (2.4) | 2/29 (6.9) | 3/177 (1.7) | 0.144 | | Glucose, mmol/L | | | | <0.001 | | <3.9 | 35/212 (16.5) | 0/26 (0) | 35/176 (19.9) | 0.006 | | 3.9–6.1 | 84/212 (39.6) | 5/26 (19.2) | 79/176 (44.9) | 0.020 | | >6.1 | 83/212 (39.2) | 21/26 (80.8) | 62/176 (35.2) | <0.001 |
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†Data were missing for lactate dehydrogenase in 152 (71.6%).
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