Advances in Virology

Xenotropic and Other Murine Leukemia Virus-Related Viruses in Humans


Publishing date
01 Nov 2011
Status
Published
Submission deadline
01 May 2011

Lead Editor

1Laboratory of Retroviruses, Center for Biologics Research and Review, Food and Drug Administration, 8800 Rockville Pike, HFM-454, Building 29B, room 4NN10, Bethesda, ME, USA

2Jefferiss Research Trust Laboratories, Wright-Fleming Institute, Faculty of Medicine, Imperial College London, St. Mary's Campus, Norfolk Place, Norfolk W2 1PG, UK

3Department of AIDS Research, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan

4Laboratory of Molecular Biology, Clinical Research Institute of Montreal, University of Montreal, 110, Pine Avenue West Montreal, QC, Canada H2W 1R7


Xenotropic and Other Murine Leukemia Virus-Related Viruses in Humans

Description

XMRV is a new human retrovirus that was originally reported in patients with prostate cancer and chronic fatigue syndrome. Subsequent reports of failure/success to detect XMRV in similar patient populations by others have resulted in the current intense controversy related to the possible association of XMRV and these human diseases. Additionally, there are potential public health implications regarding XMRV transmission by blood transfusion. Moreover, murine retrovirus sequences related to polytropic murine leukemia viruses (MLVs) have recently been reported in some human samples.

The main focus of this special issue is presenting critical research toward development and standardization of sensitive assays for the detection of XMRV and related MLVs, understanding virus biology, and investigating virus transmission, with the important goals of investigating the risk of human infections and determining any disease associations. The special issue will be an international forum for researchers to present their most recent findings in the field, with special emphasis on results that can aid in resolving the clinical and public health concerns regarding XMRV and other MLV-related viruses in humans. The special issue will publish original research and review papers including, but are not limited to the following topics:

  • Murine leukemia viruses: background
  • Endogenous retroviruses: overview
  • Cross-species transmission of MLVs: a historical perspective
  • MLVs and host adaptations
  • Biology of murine retroviruses
  • XMRV: discovery and progress
  • XMRV: human infections
  • Gammaretroviruses: development of detection assays and standardization
  • XMRV and other related murine retroviruses in vitro studies
  • XMRV transmission: animal studies
  • Prevalence of MLVs in humans
  • Novel technologies for virus detection
  • Antiretroviral drugs and MLV infection

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/av/guidelines.html. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 787394
  • - Editorial

Xenotropic and Other Murine Leukemia Virus-Related Viruses in Humans

Arifa S. Khan | Myra McClure | ... | Paul Jolicoeur
  • Special Issue
  • - Volume 2011
  • - Article ID 268214
  • - Research Article

Prevalence of XMRV Nucleic Acid and Antibody in HIV-1-Infected Men and in Men at Risk for HIV-1 Infection

J. Spindler | J. Hackett | ... | J. W. Mellors
  • Special Issue
  • - Volume 2011
  • - Article ID 272193
  • - Research Article

Nucleic Acid, Antibody, and Virus Culture Methods to Detect Xenotropic MLV-Related Virus in Human Blood Samples

M. F. Kearney | K. Lee | ... | S. F. J. Le Grice
  • Special Issue
  • - Volume 2011
  • - Article ID 403419
  • - Review Article

Murine Leukemia Viruses: Objects and Organisms

Alan Rein
  • Special Issue
  • - Volume 2011
  • - Article ID 940210
  • - Review Article

Endogenous Murine Leukemia Viruses: Relationship to XMRV and Related Sequences Detected in Human DNA Samples

Oya Cingöz | John M. Coffin
  • Special Issue
  • - Volume 2011
  • - Article ID 975801
  • - Review Article

Naturally Occurring Polymorphisms of the Mouse Gammaretrovirus Receptors CAT-1 and XPR1 Alter Virus Tropism and Pathogenicity

Christine A. Kozak
  • Special Issue
  • - Volume 2011
  • - Article ID 797820
  • - Research Article

Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients

Krista A. Delviks-Frankenberry | Chawaree Chaipan | ... | Vinay K. Pathak
  • Special Issue
  • - Volume 2011
  • - Article ID 341294
  • - Review Article

Phylogeny-Directed Search for Murine Leukemia Virus-Like Retroviruses in Vertebrate Genomes and in Patients Suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Prostate Cancer

Jonas Blomberg | Ali Sheikholvaezin | ... | Göran Sperber
  • Special Issue
  • - Volume 2011
  • - Article ID 432837
  • - Review Article

XMRV Discovery and Prostate Cancer-Related Research

David E. Kang | Michael C. Lee | ... | Robert H. Silverman
  • Special Issue
  • - Volume 2011
  • - Article ID 813651
  • - Review Article

MoMuLV-ts-1: A Unique Mouse Model of Retrovirus-Induced Lymphoma Transmitted by Breast Milk

J. Chakraborty | H. Okonta | ... | J. Duggan
Advances in Virology
 Journal metrics
Acceptance rate14%
Submission to final decision45 days
Acceptance to publication23 days
CiteScore1.970
Impact Factor-
 Submit

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.