Crystal Structure and Antitumor Activity of the Novel Zwitterionic Complex of tri- 𝑛 -Butyltin(IV) with 2-Thiobarbituric Acid

Figure 3

Binding sites of inhibitor 1 in lipoxygenase. The “walls” of this binding pocket concist of the amino acid residues: ESI : 76ALA, 533ARG, 767ARG, 128ASN, 769ASN, 760ASP, 768ASP, 78GLU, 75GLY, 249LEU, 110LYS, 15MET, 108PHE, 762VAL; EI : 76ALA, 533ARG, 767ARG, 128ASN, 760ASP, 768ASP, 761GLU, 247GLY, 248HIS, 246LEU, 249LEU, 110LYS, 762VAL.

(a)

(b)