Equilibrium and Kinetic Investigations of the Interaction of Model Platinum(II) Complex with DNA Constituents in Reference to the Antitumour Activity: Complex-Formation Reactions of [Pd(N,N-diethylethylenediamine)(H<sub>2</sub>O)<sub>2</sub>]<sup>2+</sup> with Ligands of Biological Significance and Displacement Reactions of DNA Constituents

<table>Concentration distribution diagram for the hydrolysis of <math id="M114" xmlns="http://www.w3.org/1998/Math/MathML"><msup><mrow><mrow><mo stretchy="false">[</mo><mrow><mtext>Pd</mtext><mrow><mo stretchy="false">(</mo><mrow><mtext>DEEN</mtext></mrow><mo stretchy="false">)</mo></mrow><msub><mrow><mrow><mo stretchy="false">(</mo><mrow><msub><mrow><mtext>H</mtext></mrow><mrow><mn>2</mn></mrow></msub><mtext>O</mtext></mrow><mo stretchy="false">)</mo></mrow></mrow><mrow><mn>2</mn></mrow></msub></mrow><mo stretchy="false">]</mo></mrow></mrow><mrow><mn>2</mn><mo>+</mo></mrow></msup><mo>.</mo></math></table>

Bioinorganic Chemistry and Applications

fig1

Figure 1

Figure 1: Equilibrium and Kinetic Investigations of the Interaction of Model Platinum(II) Complex with DNA Constituents in Reference to the Antitumour Activity: Complex-Formation Reactions of [Pd(N,N-diethylethylenediamine)(H<sub>2</sub>O)<sub>2</sub>]<sup>2+</sup> with Ligands of Biological Significance and Displacement Reactions of DNA Constituents 

Figure 1 | Equilibrium and Kinetic Investigations of the Interaction of Model Platinum(II) Complex with DNA Constituents in Reference to the Antitumour Activity: Complex-Formation Reactions of [Pd(N,N-diethylethylenediamine)(H2O)2]2+ with Ligands of Biological Significance and Displacement Reactions of DNA Constituents 