Zinc Binding Properties of Engineered RING Finger Domain of Arkadia E3 Ubiquitin Ligase

Figure 1

(a) The schematic structure of a RING finger domain showing the “cross-brace” arrangement of the two zinc binding sites; (b) The amino acid sequence of the RING finger domain of mouse Arkadia; (c) the mutation sites, C955R and H960R, in the sequence of Arkadia RING Finger domain.

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