DNA Interaction and DNA Cleavage Studies of a New Platinum(II) Complex Containing Aliphatic and Aromatic Dinitrogen Ligands

Table 3

Binding constants (𝐾_𝑓), number of binding sites (n), and thermodynamic parameters of the Pt (II)-DNA system.

T(K)	𝑛	Log𝐾𝑓	𝐾𝑓	𝑅^2	Δ𝐺^0(kJ mol^−1)	Δ𝐻^0(kJ mol^−1)	Δ𝑆^0(J mol^-1K^°−1)
283	1.74	7.289	1.9 × 10^7	0.94	−186.42	−111.79	−263.66
288	1.421	5.965	9.22 × 10^5	0.994	−187.72	−111.79	−263.66
310	1.191	5.162	14.5 × 10^4	0.987	−193.52	−111.79	−263.66