Table of Contents Author Guidelines Submit a Manuscript
Bioinorganic Chemistry and Applications
Volume 2011, Article ID 654250, 10 pages
http://dx.doi.org/10.1155/2011/654250
Research Article

Biological and Spectral Studies of Newly Synthesized Triazole Schiff Bases and Their Si(IV), Sn(IV) Complexes

1Department of Chemistry, Kurukshetra University Kurukshetra 136 119, India
2Department of Microbiology, Kurukshetra University Kurukshetra 136 119, India

Received 11 May 2011; Accepted 21 May 2011

Academic Editor: Viktor Brabec

Copyright © 2011 Kiran Singh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. Pereyre, J. P. Quintard, and A. Rahm, Tin in Organic Synthesis, Butterworth, London, UK, 1987.
  2. D. Marton, U. Russo, D. Stivanello, and G. Tagliavini, “Preparation of benzylstannanes by zinc-mediated coupling of benzyl bromides with organotin derivatives: physicochemical characterization and crystal structures,” Organometallics, vol. 15, no. 6, pp. 1645–1650, 1996. View at Google Scholar · View at Scopus
  3. R. C. Mehrotra and A. Singh, Organometallic Chemistry: A Unified Approach, New age international, New Delhi, India, 2000.
  4. L. Pellerito and L. Nagy, “Organotin(IV)n+ complexes formed with biologically active ligands: equilibrium and structural studies, and some biological aspects,” Coordination Chemistry Reviews, vol. 224, no. 1-2, pp. 111–150, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. K. Shahid, S. Ali, and S. Shahzadi, “The chemistry, properties, and characterization of organotin(IV)complexes of 2-(N-naphthylamido)benzoic acid,” Journal of Coordination Chemistry, vol. 62, no. 17, pp. 2919–2926, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. K. C. Joshi, V. N. Pathak, and P. Arya, “Synthesis of some new fluorine containing condensed thiazoles and their fungicidal activity,” Agricultural and Biological Chemistry, vol. 41, no. 3, pp. 543–546, 1977. View at Google Scholar · View at Scopus
  7. M. Jain, S. Gaur, S. C. Diwedi, S. C. Joshi, R. V. Singh, and A. Bansal, “Nematicidal, insecticidal, antifertility, antifungal and antibacterial activities of salicylanilide sulphathiazole and its manganese, silicon and tin complexes,” Phosphorus, Sulfur and Silicon and the Related Elements, vol. 179, no. 8, pp. 1517–1537, 2004. View at Publisher · View at Google Scholar · View at Scopus
  8. K. Singh, Dharampla, and S. S. Dhiman, “Spectral studies and antimicrobial activities of organosilicon(IV) and organotin(IV) complexes of nitrogen and sulfur donor Schiff bases derived from 4-amino-5-mercapto-3-methyl-s-triazole,” Main Group Chemistry, vol. 8, no. 1, pp. 47–59, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. T. Sedaghat and Z. Shokohipour, “Synthesis and spectroscopic studies of new organotin(IV) complexes with tridentate N- and O-donor Schiff bases,” Journal of Coordination Chemistry, vol. 62, no. 23, pp. 3837–3844, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. K. Singh, P. Puri, and Dharampal, “Synthesis and spectroscopic studies of some new organometallic chelates derived from bidentate ligands,” Turkish Journal of Chemistry, vol. 34, no. 4, pp. 499–507, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Saxena and R. V. Singh, “Diorganosilicon(iv) complexes of fluoro-imines: synthetic, spectroscopic and biological aspects,” Phosphorus, Sulfur and Silicon and Related Elements, vol. 97, no. 1–4, pp. 17–26, 1994. View at Google Scholar
  12. U. N. Tripathi, G. Venubabu, M. S. Ahmad, S. S. R. Kolisetty, and A. K. Srivastava, “Synthesis, spectral and antimicrobial studies of diorganotin(IV)3(2′- hydroxyphenyl)-5-(4-substituted phenyl) pyrazolinates,” Applied Organometallic Chemistry, vol. 20, no. 10, pp. 669–676, 2006. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Singh, Dharampal, and V. Parkash, “Synthesis, spectroscopic studies, and in vitro antifungal activity of organosilicon(IV) and organotin(IV) complexes of 4-amino-5-mercapto-3-methyl-S- triazole Schiff bases,” Phosphorus, Sulfur and Silicon and the Related Elements, vol. 183, no. 11, pp. 2784–2794, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. L. Tiano, D. Fedeli, M. Moretti, and G. Falcioni, “DNA damage induced by organotins on trout-nucleated erythrocytes,” Applied Organometallic Chemistry, vol. 15, no. 7, pp. 575–580, 2001. View at Publisher · View at Google Scholar · View at Scopus
  15. N. Gerasimchuk, T. Maher, P. Durham, K. V. Domasevitch, J. Wilking, and A. Mokhir, “Tin(IV) cyanoximates: synthesis, characterization, and cytotoxicity,” Inorganic Chemistry, vol. 46, no. 18, pp. 7268–7284, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  16. M. S. Ahmad, M. Hussain, M. Hanif, S. Ali, and B. Mirza, “Synthesis, chemical characterization and biological screening for cytotoxicity and antitumor activity of organotin (IV) derivatives of 3,4-methylenedioxy 6-nitrophenylpropenoic acid,” Molecules, vol. 12, no. 10, pp. 2348–2363, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. K. Singh, Dharampal, and S. S. Dhiman, “Synthetic, structural and biological studies of organotin(IV) complexes of schiff bases derived from pyrrol-2-carboxaldehyde,” Journal of the Iranian Chemical Society, vol. 7, no. 1, pp. 243–250, 2010. View at Google Scholar · View at Scopus
  18. K. Singh and Dharampal, “Synthetic, structural and biological studies of organosilicon(IV) complexes of Schiff bases derived from pyrrole-2-carboxaldehyde,” Journal of the Serbian Chemical Society, vol. 75, no. 7, pp. 917–927, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Bala, R. P. Gupta, M. L. Sachdeva, A. Singh, and H. K. Pujari, “Heterocyclic systems containing bridgehead nitrogen atom: part XXXIII–syntheses of s-Triazolo[I,3,4] thiadiazine, s-Triazolo[3,4,b][I,3,4]thiadiazino[6,7-b]quinoxaline & as-Triazino [I,3,4]- thiadiazines,” Indian Journal of Chemistry, vol. 16, pp. 481–483, 1978. View at Google Scholar
  20. K. S. Dhaka, J. Mohan, V. K. Chadha, and H. K. Pujari, “Heterocyclic systems containing bridgehead nitrogen atom: part XVI-Syntheses of s-Triazolo[3,4-b][1,3,4] thiadiazines and related heterocycles,” Indian Journal of Chemistry, vol. 12, p. 288, 1974. View at Google Scholar
  21. G. Singh, P. A. Singh, K. Singh, D. P. Singh, R. N. Handa, and S. N. Dubey, “Synthesis and structural studies of some bivalent metal complexes with bidentate Schiff base ligands,” Proceedings of National Academy of Sciences India, vol. 72, no. A-2, pp. 87–95, 2002. View at Google Scholar
  22. P. G. Avaji, S. A. Patil, and P. S. Badami, “Synthesis, spectral, thermal, solid state d.c. electrical conductivity and biological studies of Co(II), Ni(II) and Cu(II) complexes with 3-substituted-4-amino (indole-3-aldehydo)-5-mercapto-1,2,4-triazole Schiff bases,” Journal of Coordination Chemistry, vol. 61, no. 12, pp. 1884–1896, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. B. K. Sinha, R. Singh, and J. P. Srivastava, “Substituted 1,2,4-triazoles as complexing ligands-I Ni(II), Co(II), Cu(II), Zn(II), Pd(II), Cd(II) and Pb(II) complexes with 4-amino-3,5-dimercapto-1,2,4-triazole,” Journal of Inorganic and Nuclear Chemistry, vol. 39, no. 10, pp. 1797–1801, 1977. View at Google Scholar · View at Scopus
  24. K. Singh, R. V. Singh, and J. P. Tandon, “Synthesis and structural features of organo Si(IV) imine complexes,” Polyhedron, vol. 7, no. 2, pp. 151–154, 1988. View at Google Scholar · View at Scopus
  25. S. Belwal and R. V. Singh, “Bioactive versatile azomethine complexes of organotin(IV) and organosilicon(IV),” Applied Organometallic Chemistry, vol. 12, no. 1, pp. 39–46, 1998. View at Google Scholar · View at Scopus
  26. K. Singh, D. P. Singh, M. S. Barwa, P. Tyagi, and Y. Mirza, “Antibacterial Co(II), Ni(II), Cu(II) and Zn(II) complexes of Schiff bases derived from fluorobenzaldehyde and triazoles,” Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 21, no. 5, pp. 557–562, 2006. View at Google Scholar
  27. Suresh, P. Srinivas, T. Suresh, M. Revanasiddappa, and S. Khasim, “Synthetic, spectral and thermal studies of tin(IV) complexes of 1, 5-benzodiazepines,” E-Journal of Chemistry, vol. 5, no. 3, pp. 627–633, 2008. View at Google Scholar · View at Scopus
  28. M. Nath, S. Goyal, and S. Goyal, “Synthesis, spectral and biological studies of organosilicon(IV) complexes of Schiff bases derived from amino acids,” Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry, vol. 30, no. 9, pp. 1794–1804, 2000. View at Google Scholar · View at Scopus
  29. A. Chaudhary and R. V. Singh, “Studies on biologically potent tetraazamacrocyclic complexes of bivalent tin,” Phosphorus, Sulfur and Silicon and the Related Elements, vol. 178, no. 3, pp. 615–626, 2003. View at Publisher · View at Google Scholar · View at Scopus
  30. M. Pellei, G. G. Lobbia, M. Ricciutelli, and C. Santini, “Synthesis and spectroscopic characterization of new organotin(IV) complexes with bis(3,5-dimethylpyrazol-1-yl)dithioacetate,” Journal of Coordination Chemistry, vol. 58, no. 5, pp. 409–420, 2005. View at Publisher · View at Google Scholar · View at Scopus
  31. I. Ahmad and A. Z. Beg, “Antimicrobial and phytochemical studies on 45 Indian medicinal plants against multi-drug resistant human pathogens,” Journal of Ethnopharmacology, vol. 74, no. 2, pp. 113–123, 2001. View at Publisher · View at Google Scholar · View at Scopus
  32. J. M. Andrews, “Determination of minimum inhibitory concentrations,” Journal of Antimicrobial Chemotherapy, vol. 48, no. 1, pp. 5–16, 2001. View at Google Scholar · View at Scopus
  33. NCCLS, Method for Dilution Antimicrobial Susceptibility Test for Bacteria That Grow Aerobically, Approved Standards, National Committee for Clinical Standards, Villanova, Pa, USA, 5th edition, 2000.
  34. K. R. Aneja, C. Sharma, and R. Joshi, “Fungal infection of the ear: a common problem in the north eastern part of Haryana,” International Journal of Otorhinolaryngology, vol. 74, no. 6, pp. 604–607, 2010. View at Google Scholar
  35. S. K. S. Al-Burtamani, M. O. Fatope, R. G. Marwah, A. K. Onifade, and S. H. Al-Saidi, “Chemical composition, antibacterial and antifungal activities of the essential oil of Haplophyllum tuberculatum from Oman,” Journal of Ethnopharmacology, vol. 96, no. 1-2, pp. 107–112, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus