Metal-Based Biologically Active Compounds: Synthesis, Spectral, and Antimicrobial Studies of Cobalt, Nickel, Copper, and Zinc Complexes of Triazole-Derived Schiff Bases
Table 5
Antibacterial activity of synthesized compounds.
Compound
Diameter of growth of inhibition zone
(mm)a
Staphylococcus aureus
Bacillus subtilis
HL1
19.0
21.3
Co(L1)(OAc)·3H2O
23.6
25.6
Co(L1)2·2H2O
16.6
19.6
Ni(L1)(OAc)·3H2O
16.3
18.3
Ni(L1)2·2H2O
14.6
19.6
Cu(L1)(OAc)·H2O
20.3
18.3
Cu(L1)2
15.6
17.0
Zn(L1)(OAc)·3H2O
20.6
23.6
Zn(L1)2·2H2O
19.3
20.6
HL2
17.3
18.3
Co(L2)(OAc)·3H2O
16.6
19.3
Co(L2)2·2H2O
17.6
20.6
Ni(L2)(OAc)·3H2O
15.6
18.3
Ni(L2)2·2H2O
15.0
16.6
Cu(L2)(OAc)·H2O
16.3
18.5
Cu(L2)2
19.6
21.2
Zn(L2)(OAc)·3H2O
20.3
21.6
Zn(L2)2·2H2O
18.3
19.6
Ciprofloxacin
26.6
24.0
aValues, including diameter of the well (8 mm), are means of three replicates.